Lenalidomide for the treatment of relapsed and refractory multiple myeloma

Lenalidomide is an amino-substituted derivative of thalidomide with direct antiproliferative and cytotoxic effects on the myeloma tumor cell, as well as antiangiogenic activity and immunomodulatory effects. Together with the introduction of bortezomib and thalidomide, lenalidomide has significantly...

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Dettagli Bibliografici
Autori principali: van de Donk, Niels WCJ, Görgün, Güllü, Groen, Richard WJ, Jakubikova, Jana, Mitsiades, Constantine S, Hideshima, Teru, Laubach, Jacob, Nijhof, Inger S, Raymakers, Reinier A, Lokhorst, Henk M, Richardson, Paul G, Anderson, Kenneth C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2012
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430086/
https://ncbi.nlm.nih.gov/pubmed/22956884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S27087
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