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Lenalidomide for the treatment of relapsed and refractory multiple myeloma
Lenalidomide is an amino-substituted derivative of thalidomide with direct antiproliferative and cytotoxic effects on the myeloma tumor cell, as well as antiangiogenic activity and immunomodulatory effects. Together with the introduction of bortezomib and thalidomide, lenalidomide has significantly...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Dove Medical Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430086/ https://ncbi.nlm.nih.gov/pubmed/22956884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S27087 |
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