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Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents

Multiple Myeloma (MM), a malignancy of plasma cells, remains incurable despite the use of conventional and novel therapies. Halofuginone (HF), a synthetic derivative of quinazolinone alkaloid, has recently been shown to have anti-cancer activity in various preclinical settings. This study demonstrat...

詳細記述

保存先:
書誌詳細
出版年:Br J Haematol
主要な著者: Leiba, Merav, Jakubikova, Jana, Klippel, Steffen, Mitsiades, Constantine S., Hideshima, Teru, Tai, Yu-Tzu, Leiba, Adi, Pines, Mark, Richardson, Paul G., Nagler, Arnon, Anderson, Kenneth C.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414398/
https://ncbi.nlm.nih.gov/pubmed/22533681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2012.09120.x
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