Increased Survival in B-Cell-Deficient Mice during Experimental Cerebral Malaria Suggests a Role for Circulating Immune Complexes

Por de Oliveira, Rosane B., Wang, Jennifer P., Ram, Sanjay, Gazzinelli, Ricardo T., Finberg, Robert W., Golenbock, Douglas T.
Publicado em 2014

Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: lessons from the pathogenic Neisseriae

Por Ram, Sanjay, Shaughnessy, Jutamas, DeOliveira, Rosane B., Lewis, Lisa A., Gulati, Sunita, Rice, Peter A.
Publicado no Immunobiology (2016)

Gonococcal lipooligosaccharide sialylation: virulence factor and target for novel immunotherapeutics

Por Ram, Sanjay, Shaughnessy, Jutamas, de Oliveira, Rosane B., Lewis, Lisa A., Gulati, Sunita, Rice, Peter A.
Publicado no Pathog Dis (2017)

Fusion Protein Comprising Factor H Domains 6 and 7 and Human IgG1 Fc as an Antibacterial Immunotherapeutic

Por Shaughnessy, Jutamas, Vu, David M., Punjabi, Rahi, Serra-Pladevall, Judit, DeOliveira, Rosane B., Granoff, Dan M., Ram, Sanjay
Publicado no Clin Vaccine Immunol (2014)

Hemolysis-induced lethality involves inflammasome activation by heme

Por Dutra, Fabianno F., Alves, Letícia S., Rodrigues, Danielle, Fernandez, Patricia L., de Oliveira, Rosane B., Golenbock, Douglas T., Zamboni, Dario S., Bozza, Marcelo T.
Publicado em 2014

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodial-derived hemozoin and DNA during malaria

Por Kalantari, Parisa, DeOliveira, Rosane B., Chan, Jennie, Corbett, Yolanda, Rathinam, Vijay, Stutz, Andrea, Latz, Eicke, Gazzinelli, Ricardo T., Golenbock, Douglas T., Fitzgerald, Katherine A.
Publicado em 2014

Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae

Por Shaughnessy, Jutamas, Tran, Y, Zheng, Bo, DeOliveira, Rosane B., Gulati, Sunita, Song, Wen-Chao, Maclean, James M., Wycoff, Keith L., Ram, Sanjay
Publicado no Front Immunol (2020)

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

Por Franklin, Bernardo S., Ishizaka, Sally T., Lamphier, Marc, Gusovsky, Fabian, Hansen, Hans, Rose, Jeffrey, Zheng, Wanjun, Ataíde, Marco Antônio, de Oliveira, Rosane B., Golenbock, Douglas T., Gazzinelli, Ricardo T.
Publicado em 2011

Interferon-γ and Granulocyte/Monocyte Colony-stimulating Factor Production by Natural Killer Cells Involves Different Signaling Pathways and the Adaptor Stimulator of Interferon Ge...

Por Souza-Fonseca-Guimaraes, Fernando, Parlato, Marianna, de Oliveira, Rosane B., Golenbock, Douglas, Fitzgerald, Katherine, Shalova, Irina N., Biswas, Subhra K., Cavaillon, Jean-Marc, Adib-Conquy, Minou
Publicado em 2013

Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine

Por Gulati, Sunita, Pennington, Michael W., Czerwinski, Andrzej, Carter, Darrick, Zheng, Bo, Nowak, Nancy A., DeOliveira, Rosane B., Shaughnessy, Jutamas, Reed, George W., Ram, Sanjay, Rice, Peter A.
Publicado no mBio (2019)

Human factor H domains 6 and 7 fused to IgG1 Fc are immunotherapeutic against Neisseria gonorrhoeae

Por Shaughnessy, Jutamas, Lewis, Lisa A., Zheng, Bo, Carr, Caleb, Bass, Isaac, Gulati, Sunita, DeOliveira, Rosane B., Gose, Severin, Reed, George W., Botto, Marina, Rice, Peter A., Ram, Sanjay
Publicado no J Immunol (2018)

Malaria primes the innate immune response due to interferon-γ induced enhancement of toll-like receptor expression and function

Por Franklin, Bernardo S., Parroche, Peggy, Ataíde, Marco Antǒnio, Lauw, Fanny, Ropert, Catherine, de Oliveira, Rosane B., Pereira, Dhelio, Tada, Mauro Shugiro, Nogueira, Paulo, da Silva, Luiz Hildebrando Pereira, Bjorkbacka, Harry, Golenbock, Douglas T., Gazzinelli, Ricardo T.
Publicado em 2009

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

Por Sharma, Shruti, DeOliveira, Rosane B., Kalantari, Parisa, Parroche, Peggy, Goutagny, Nadege, Jiang, Zhaozhao, Chan, Jennie, Bartholomeu, Daniella C., Lauw, Fanny, Hall, J. Perry, Barber, Glen N., Gazzinelli, Ricardo T., Fitzgerald, Katherine A., Golenbock, Douglas T.
Publicado em 2011

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14(+) CD16(+) CD64(high) CD32(low) Inflammatory Monocytes from Malaria Patients

Por Hirako, Isabella C., Gallego-Marin, Carolina, Ataide, Marco A., Andrade, Warrison A., Gravina, Humberto, Rocha, Bruno C., de Oliveira, Rosane B., Pereira, Dhelio B., Vinetz, Joseph, Diamond, Betty, Ram, Sanjay, Golenbock, Douglas T., Gazzinelli, Ricardo T.
Publicado no mBio (2015)

A Novel Sialylation Site on Neisseria gonorrhoeae Lipooligosaccharide Links Heptose II Lactose Expression with Pathogenicity

Por Ram, Sanjay, Gulati, Sunita, Lewis, Lisa A., Chakraborti, Srinjoy, Zheng, Bo, DeOliveira, Rosane B., Reed, George W., Cox, Andrew D., Li, Jianjun, St. Michael, Frank, Stupak, Jacek, Su, Xiao-Hong, Saha, Sudeshna, Landig, Corinna S., Varki, Ajit, Rice, Peter A.
Publicado no Infect Immun (2018)

RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages

Por Gupta, Rahul, Ghosh, Shubhendu, Monks, Brian, DeOliveira, Rosane B., Tzeng, Te-Chen, Kalantari, Parisa, Nandy, Anubhab, Bhattacharjee, Bornali, Chan, Jennie, Ferreira, Fabianno, Rathinam, Vijay, Sharma, Shruti, Lien, Egil, Silverman, Neal, Fitzgerald, Katherine, Firon, Arnaud, Trieu-Cuot, Patrick, Henneke, Philipp, Golenbock, Douglas T.
Publicado em 2014

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody

Por Gulati, Sunita, Beurskens, Frank J., de Kreuk, Bart-Jan, Roza, Marcel, Zheng, Bo, DeOliveira, Rosane B., Shaughnessy, Jutamas, Nowak, Nancy A., Taylor, Ronald P., Botto, Marina, He, Xianbao, Ingalls, Robin R., Woodruff, Trent M., Song, Wen-Chao, Schuurman, Janine, Rice, Peter A., Ram, Sanjay
Publicado no PLoS Biol (2019)

Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens

Por Cywes-Bentley, Colette, Skurnik, David, Zaidi, Tanweer, Roux, Damien, DeOliveira, Rosane B., Garrett, Wendy S., Lu, Xi, O’Malley, Jennifer, Kinzel, Kathryn, Zaidi, Tauqeer, Rey, Astrid, Perrin, Christophe, Fichorova, Raina N., Kayatani, Alexander K. K., Maira-Litràn, Tomas, Gening, Marina L., Tsvetkov, Yury E., Nifantiev, Nikolay E., Bakaletz, Lauren O., Pelton, Stephen I., Golenbock, Douglas T., Pier, Gerald B.
Publicado em 2013