Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

Although Toll-like receptor 9 (TLR9) has been implicated in regulating cytokine and type I interferon (IFN) production during malaria in humans and mice, the high AT content of the Plasmodium falciparum genome prompted us to examine the possibility that malarial DNA triggered TLR9-independent DNA se...

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Detalhes bibliográficos
Main Authors: Sharma, Shruti, DeOliveira, Rosane B., Kalantari, Parisa, Parroche, Peggy, Goutagny, Nadege, Jiang, Zhaozhao, Chan, Jennie, Bartholomeu, Daniella C., Lauw, Fanny, Hall, J. Perry, Barber, Glen N., Gazzinelli, Ricardo T., Fitzgerald, Katherine A., Golenbock, Douglas T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162998/
https://ncbi.nlm.nih.gov/pubmed/21820332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.016
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