Malaria primes the innate immune response due to interferon-γ induced enhancement of toll-like receptor expression and function

Malaria-induced sepsis is associated with an intense proinflammatory cytokinemia for which the underlying mechanisms are poorly understood. It has been demonstrated that experimental infection of humans with Plasmodium falciparum primes Toll-like receptor (TLR)-mediated proinflammatory responses. Ne...

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Autors principals: Franklin, Bernardo S., Parroche, Peggy, Ataíde, Marco Antǒnio, Lauw, Fanny, Ropert, Catherine, de Oliveira, Rosane B., Pereira, Dhelio, Tada, Mauro Shugiro, Nogueira, Paulo, da Silva, Luiz Hildebrando Pereira, Bjorkbacka, Harry, Golenbock, Douglas T., Gazzinelli, Ricardo T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657593/
https://ncbi.nlm.nih.gov/pubmed/19297619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809742106
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