Malaria primes the innate immune response due to interferon-γ induced enhancement of toll-like receptor expression and function

Malaria-induced sepsis is associated with an intense proinflammatory cytokinemia for which the underlying mechanisms are poorly understood. It has been demonstrated that experimental infection of humans with Plasmodium falciparum primes Toll-like receptor (TLR)-mediated proinflammatory responses. Ne...

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Main Authors: Franklin, Bernardo S., Parroche, Peggy, Ataíde, Marco Antǒnio, Lauw, Fanny, Ropert, Catherine, de Oliveira, Rosane B., Pereira, Dhelio, Tada, Mauro Shugiro, Nogueira, Paulo, da Silva, Luiz Hildebrando Pereira, Bjorkbacka, Harry, Golenbock, Douglas T., Gazzinelli, Ricardo T.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657593/
https://ncbi.nlm.nih.gov/pubmed/19297619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809742106
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