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Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria
Excessive release of proinflammatory cytokines by innate immune cells is an important component of the pathogenic basis of malaria. Proinflammatory cytokines are a direct output of Toll-like receptor (TLR) activation during microbial infection. Thus, interference with TLR function is likely to rende...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048158/ https://ncbi.nlm.nih.gov/pubmed/21303985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015406108 |
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