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Regulation of the nucleic acid-sensing Toll-like receptors

Many of the ligands for Toll-like receptors (TLRs) are unique to microorganisms, such that receptor activation unequivocally indicates the presence of something foreign. However, a subset of TLRs recognizes nucleic acids, which are present in both the host and foreign microorganisms. This specificit...

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Pubblicato in:Nat Rev Immunol
Autori principali: Lind, Nicholas A., Rael, Victoria E., Pestal, Kathleen, Liu, Bo, Barton, Gregory M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283745/
https://ncbi.nlm.nih.gov/pubmed/34272507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-021-00577-0
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