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Nucleic acid-sensing TLRs: Trafficking and regulation

Toll-like receptors (TLRs) play an important role in innate immune responses against pathogenic microorganisms or tissue damage. Nucleic acid (NA)-sensing TLRs localize in intracellular vesicular compartments and recognize foreign- and host-derived nucleotides. Inappropriate activation of NA-sensing...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Majer, Olivia, Liu, Bo, Barton, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446938/
https://ncbi.nlm.nih.gov/pubmed/27907816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.10.003
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