Development of Complement Factor H–Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae

Novel therapeutics against the global threat of multidrug-resistant Neisseria gonorrhoeae are urgently needed. Gonococci possess several mechanisms to evade killing by human complement, including binding of factor H (FH), a key inhibitor of the alternative pathway. FH comprises 20 short consensus re...

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Publicado en:Front Immunol
Main Authors: Shaughnessy, Jutamas, Tran, Y, Zheng, Bo, DeOliveira, Rosane B., Gulati, Sunita, Song, Wen-Chao, Maclean, James M., Wycoff, Keith L., Ram, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649208/
https://ncbi.nlm.nih.gov/pubmed/33193396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583305
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