Factor H facilitates adherence of Neisseria gonorrhoeae to complement receptor 3 on eukaryotic cells

Neisseria gonorrhoeae can engage human complement receptor 3 (CR3) directly or through surface-bound iC3b. Factor H (fH) that binds to bacteria facilitates conversion of C3b to iC3b. fH also binds directly to CR3 on professional phagocytes. Certain non-professional phagocytes such as primary cervica...

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Bibliographic Details
Main Authors: Agarwal, Sarika, Ram, Sanjay, Ngampasutadol, Jutamas, Gulati, Sunita, Zipfel, Peter F., Rice, Peter A.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944003/
https://ncbi.nlm.nih.gov/pubmed/20826755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904191
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