Active intermediates in heme mono reactions as revealed by cryoreduction/annealing, EPR/ENDOR studies

Por Davydov, Roman, Hoffman, Brian M.
Publicado em 2010

Use of deuterated camphor as substrate in (1)H ENDOR studies of hydroxylation by cryoreduced oxy P450cam provides new evidence for the involvement of compound I

Por Davydov, Roman, Dawson, John H., Perera, Roshan, Hoffman, Brian M.
Publicado em 2013

Characterization of the Microsomal Cytochrome P450 2B4 O(2)-Activation Intermediates by Cryoreduction/EPR.

Por Davydov, Roman, Razeghifard, Reza, Im, Sang-Choul, Waskell, Lucy, Hoffman, Brian M.
Publicado em 2008

Comparison of the mechanisms of heme hydroxylation by heme oxygenases-1 and -2: kinetic and cryoreduction studies

Por Davydov, Roman, Fleischhacker, Angela S., Bagai, Ireena, Hoffman, Brian M., Ragsdale, Stephen W.
Publicado no Biochemistry (2015)

Spectroscopic and Crystallographic Evidence for the Role of a Water-Containing H-Bond Network in Oxidase Activity of an Engineered Myoglobin

Por Petrik, Igor D., Davydov, Roman, Ross, Matthew, Zhao, Xuan, Hoffman, Brian, Lu, Yi
Publicado no J Am Chem Soc (2015)

Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc (CYP11A1): EPR / ENDOR/cryoreductio...

Por Davydov, Roman, Gilep, Andrey A., Strushkevich, Natallia V., Usanov, Sergey A., Hoffman, Brian M.
Publicado em 2012

Probing the oxyferrous and catalytically active ferryl states of Amphitrite ornata dehaloperoxidase by cryoreduction and EPR/ENDOR spectroscopy. Detection of Compound I

Por Davydov, Roman, Osborne, Robert L., Shanmugam, Muralidharan, Du, Jing, Dawson, John H., Hoffman, Brian M.
Publicado em 2010

Generation of High-Spin Iron(I) in a Protein Environment Using Cryoreduction

Por Davydov, Roman M., McLaughlin, Matthew P., Bill, Eckhard, Hoffman, Brian M., Holland, Patrick L.
Publicado em 2013

Electron Paramagnetic Resonance and Electron-Nuclear Double Resonance Studies of the Reactions of Cryogenerated Hydroperoxoferric–Hemoprotein Intermediates

Por Davydov, Roman, Laryukhin, Mikhail, Ledbetter-Rogers, Amy, Sono, Masanori, Dawson, John H., Hoffman, Brian M.
Publicado em 2014

Evidence that Compound I is the active species in both the hydroxylase and lyase steps by which P450scc converts cholesterol to pregnenolone: EPR/ENDOR/cryoreduction/annealing stud...

Por Davydov, Roman, Strushkevich, Natallia, Smil, David, Yantsevich, Aliaksei, Gilep, Andrey, Usanov, Sergey, Hoffman, Brian M.
Publicado no Biochemistry (2015)

Identification of a hemerythrin-like domain in a P(1B)-type transport ATPase

Por Traverso, Matthew E., Subramanian, Poorna, Davydov, Roman, Hoffman, Brian M., Stemmler, Timothy L., Rosenzweig, Amy C.
Publicado em 2010

Distinct Reaction Pathways followed Upon Reduction of Oxy-Heme Oxygenase and Oxy-Myoglobin as Characterized by Mössbauer Spectroscopy

Por Garcia-Serres, Ricardo, Davydov, Roman M., Matsui, Toshitaka, Ikeda-Saito, Masao, Hoffman, Brian M., Huynh, Boi Hanh
Publicado em 2007

The role of the proximal cysteine hydrogen bonding interaction in cytochrome P450 2B4 studied by cryoreduction/EPR/ENDOR spectroscopy

Por Davydov, Roman, Im, Sangchoul, Shanmugam, Muralidharam, Gunderson, William A., Pearl, Naw May, Hoffman, Brian M., Waskell, Lucy
Publicado no Biochemistry (2016)

Enzymatic and Cryoreduction EPR Studies of the Hydroxylation of Methylated N(ω)-Hydroxy-l-arginine Analogues by Nitric Oxide Synthase from Geobacillus stearothermophilus

Por Davydov, Roman, Labby, Kristin Jansen, Chobot, Sarah E., Lukoyanov, Dmitriy A., Crane, Brian R., Silverman, Richard B., Hoffman, Brian M.
Publicado em 2014

Exploring Electron/Proton Transfer and Conformational Changes in the Nitrogenase MoFe Protein and FeMo-cofactor Through Cryoreduction/EPR Measurements

Por Davydov, Roman, Khadka, Nimesh, Yang, Zhi-Yong, Fielding, Andrew J., Lukoyanov, Dmitriy, Dean, Dennis R., Seefeldt, Lance C., Hoffman, Brian M.
Publicado no Isr J Chem (2016)

Dioxygen Activation at Non-Heme Diiron Centers: Oxidation of a Proximal Residue in the I100W Variant of Toluene/o-Xylene Monooxygenase Hydroxylase

Por Murray, Leslie J., García-Serres, Ricardo, McCormick, Michael S., Davydov, Roman, Naik, Sunil, Kim, Sun-Hee, Hoffman, Brian M., Huynh, Boi Hanh, Lippard, Stephen J.
Publicado em 2007

Characterization and Structure of a Zn(2+) and [2Fe-2S]-containing Copper Chaperone from Archaeoglobus fulgidus

Por Sazinsky, Matthew H., LeMoine, Benjamin, Orofino, Maria, Davydov, Roman, Bencze, Krisztina Z., Stemmler, Timothy L., Hoffman, Brian M., Argüello, José M., Rosenzweig, Amy C.
Publicado em 2007

Probing the Ternary Complexes of Indoleamine and Tryptophan 2,3-Dioxygenases by Cryoreduction EPR and ENDOR Spectroscopy

Por Davydov, Roman M., Chauhan, Nishma, Thackray, Sarah J., Anderson, J. L. Ross, Papadopoulou, Nektaria D., Mowat, Christopher G., Chapman, Stephen K., Raven, Emma L., Hoffman, Brian M.
Publicado em 2010