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Probing the Ternary Complexes of Indoleamine and Tryptophan 2,3-Dioxygenases by Cryoreduction EPR and ENDOR Spectroscopy

[Image: see text] We have applied cryoreduction/EPR/ENDOR techniques to characterize the active-site structure of the ferrous-oxy complexes of human (hIDO) and Shewanella oneidensis (sIDO) indoleamine 2,3-dioxygenases, Xanthomonas campestris (XcTDO) tryptophan 2,3-dioxygenase, and the H55S variant o...

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Detalhes bibliográficos
Main Authors: Davydov, Roman M., Chauhan, Nishma, Thackray, Sarah J., Anderson, J. L. Ross, Papadopoulou, Nektaria D., Mowat, Christopher G., Chapman, Stephen K., Raven, Emma L., Hoffman, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903012/
https://ncbi.nlm.nih.gov/pubmed/20353179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100518z
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