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Substrate Stereo-specificity in Tryptophan dioxygenase and Indoleamine 2,3- dioxygenase
The first and rate-limiting step of the kynurenine pathway, in which tryptophan (Trp) is converted to N-formylkynurenine is catalyzed by two heme-containing proteins, Indoleamine 2,3-dioxygenase (IDO) and Tryptophan 2,3-dioxygenase (TDO). In mammals, TDO is found exclusively in liver tissue, IDO is...
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| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939288/ https://ncbi.nlm.nih.gov/pubmed/20715188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22819 |
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