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Spectroscopic Studies of Ligand and Substrate Binding to Human Indoleamine 2,3-Dioxygenase
Human indoleamine 2,3-dioxygenase (hIDO) is an intracellular heme-containing enzyme, which catalyzes the initial and rate-determining step of L-tryptophan (L-Trp) metabolism via the kynurenine pathway in nonhepatic tissues. Steady-state kinetic data showed that hIDO exhibits substrate inhibition beh...
में बचाया:
| में प्रकाशित: | Biochemistry |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5450916/ https://ncbi.nlm.nih.gov/pubmed/20476772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1005078 |
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