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Ferryl Derivatives of Human Indoleamine 2,3-Dioxygenase

The critical role of the ferryl intermediate in catalyzing the oxygen chemistry of monooxygenases, oxidases, or peroxidases has been known for decades. In contrast, its involvement in heme-based dioxygenases, such as human indoleamine 2,3-dioxygenase (hIDO), was not recognized until recently. In thi...

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Autori principali: Lu, Changyuan, Yeh, Syun-Ru
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283129/
https://ncbi.nlm.nih.gov/pubmed/21502325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221507
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