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Ligand and Substrate Migration in Human Indoleamine 2,3-Dioxygenase
Human indoleamine 2,3-dioxygenase (hIDO), a monomeric heme enzyme, catalyzes the oxidative degradation of l-Trp and other indoleamine derivatives. Using Fourier transform infrared and optical absorption spectroscopy, we have investigated the interplay between ferrous hIDO, the ligand analog CO, and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797224/ https://ncbi.nlm.nih.gov/pubmed/19767648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.039859 |
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