Exploring the mechanism of tryptophan 2,3-dioxygenase

Autor Thackray, Sarah J., Mowat, Christopher G., Chapman, Stephen K.
Vydáno 2008

Structure and Reaction Mechanism in the Heme Dioxygenases

Autor Efimov, Igor, Basran, Jaswir, Thackray, Sarah J., Handa, Sandeep, Mowat, Christopher G., Raven, Emma Lloyd
Vydáno 2011

The Mechanism of Substrate Inhibition in Human Indoleamine 2,3-Dioxygenase

Autor Efimov, Igor, Basran, Jaswir, Sun, Xiao, Chauhan, Nishma, Chapman, Stephen K., Mowat, Christopher G., Raven, Emma Lloyd
Vydáno 2012

The Mechanism of Formation of N-Formylkynurenine by Heme Dioxygenases

Autor Basran, Jaswir, Efimov, Igor, Chauhan, Nishma, Thackray, Sarah J., Krupa, James L., Eaton, Graham, Griffith, Gerry A., Mowat, Christopher G., Handa, Sandeep, Raven, Emma Lloyd
Vydáno 2011

Probing the Ternary Complexes of Indoleamine and Tryptophan 2,3-Dioxygenases by Cryoreduction EPR and ENDOR Spectroscopy

Autor Davydov, Roman M., Chauhan, Nishma, Thackray, Sarah J., Anderson, J. L. Ross, Papadopoulou, Nektaria D., Mowat, Christopher G., Chapman, Stephen K., Raven, Emma L., Hoffman, Brian M.
Vydáno 2010

Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase

Autor Hutchinson, Jonathan P., Rowland, Paul, Taylor, Mark R. D., Christodoulou, Erica M., Haslam, Carl, Hobbs, Clare I., Holmes, Duncan S., Homes, Paul, Liddle, John, Mole, Damian J., Uings, Iain, Walker, Ann L., Webster, Scott P., Mowat, Christopher G., Chung, Chun-wa
Vydáno v Nat Commun (2017)

Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

Autor Forouhar, Farhad, Anderson, J. L. Ross, Mowat, Christopher G., Vorobiev, Sergey M., Hussain, Arif, Abashidze, Mariam, Bruckmann, Chiara, Thackray, Sarah J., Seetharaman, Jayaraman, Tucker, Todd, Xiao, Rong, Ma, Li-Chung, Zhao, Li, Acton, Thomas B., Montelione, Gaetano T., Chapman, Stephen K., Tong, Liang
Vydáno 2007

Kynurenine–3–monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

Autor Mole, Damian J, Webster, Scott P, Uings, Iain, Zheng, Xiaozhong, Binnie, Margaret, Wilson, Kris, Hutchinson, Jonathan P, Mirguet, Olivier, Walker, Ann, Beaufils, Benjamin, Ancellin, Nicolas, Trottet, Lionel, Bénéton, Véronique, Mowat, Christopher G, Wilkinson, Martin, Rowland, Paul, Haslam, Carl, McBride, Andrew, Homer, Natalie ZM, Baily, James E, Sharp, Matthew GF, Garden, O James, Hughes, Jeremy, Howie, Sarah EM, Holmes, Duncan S, Liddle, John, Iredale, John P
Vydáno v Nat Med (2016)