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The Mechanism of Formation of N-Formylkynurenine by Heme Dioxygenases
[Image: see text] Heme dioxygenases catalyze the oxidation of l-tryptophan to N-formylkynurenine (NFK), the first and rate-limiting step in tryptophan catabolism. Although recent progress has been made on early stages in the mechanism, there is currently no experimental data on the mechanism of prod...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210546/ https://ncbi.nlm.nih.gov/pubmed/21892828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja207066z |
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