Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

Tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) constitute an important, yet relatively poorly understood, family of heme-containing enzymes. Here, we report extensive structural and biochemical studies of the Xanthomonas campestris TDO and a related protein SO4414 from Shewan...

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Detalhes bibliográficos
Main Authors: Forouhar, Farhad, Anderson, J. L. Ross, Mowat, Christopher G., Vorobiev, Sergey M., Hussain, Arif, Abashidze, Mariam, Bruckmann, Chiara, Thackray, Sarah J., Seetharaman, Jayaraman, Tucker, Todd, Xiao, Rong, Ma, Li-Chung, Zhao, Li, Acton, Thomas B., Montelione, Gaetano T., Chapman, Stephen K., Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766409/
https://ncbi.nlm.nih.gov/pubmed/17197414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610007104
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