Oral Efficacy of a Respiratory Syncytial Virus Inhibitor in Rodent Models of Infection

Por Cianci, Christopher, Genovesi, Eugene V., Lamb, Lucinda, Medina, Ivette, Yang, Zheng, Zadjura, Lisa, Yang, Hyekyung, D'Arienzo, Celia, Sin, Ny, Yu, Kuo-Long, Combrink, Keith, Li, Zhufang, Colonno, Richard, Meanwell, Nicholas, Clark, Junius, Krystal, Mark
Publicado em 2004

Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors

Por Liu, Chunjian, Lin, James, Moslin, Ryan, Tokarski, John S., Muckelbauer, Jodi, Chang, ChiehYing, Tredup, Jeffrey, Xie, Dianlin, Park, Hyunsoo, Li, Peng, Wu, Dauh-Rurng, Strnad, Joann, Zupa-Fernandez, Adriana, Cheng, Lihong, Chaudhry, Charu, Chen, Jing, Chen, Cliff, Sun, Huadong, Elzinga, Paul, D’arienzo, Celia, Gillooly, Kathleen, Taylor, Tracy L., McIntyre, Kim W., Salter-Cid, Luisa, Lombardo, Louis J., Carter, Percy H., Aranibar, Nelly, Burke, James R., Weinstein, David S.
Publicado no ACS Med Chem Lett (2019)

Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P(1) Receptor Modulator in Clinical Trials

Por Dhar, T. G. Murali, Xiao, Hai-Yun, Xie, Jenny, Lehman-McKeeman, Lois D., Wu, Dauh-Rurng, Dabros, Marta, Yang, Xiaoxia, Taylor, Tracy L., Zhou, Xia D., Heimrich, Elizabeth M., Thomas, Rochelle, McIntyre, Kim W., Warrack, Bethanne, Shi, Hong, Levesque, Paul C., Zhu, Jia L., Hennan, James, Balimane, Praveen, Yang, Zheng, Marino, Anthony M., Cornelius, Georgia, D’Arienzo, Celia J., Mathur, Arvind, Shen, Ding Ren, Cvijic, Mary Ellen, Salter-Cid, Luisa, Barrish, Joel C., Carter, Percy H., Dyckman, Alaric J.
Publicado no ACS Med Chem Lett (2016)

Identification of potent tricyclic prodrug S1P(1) receptor modulators

Por Marcoux, David, Xiao, Hai-Yun, Murali Dhar, T. G., Xie, Jenny, Lehman-McKeeman, Lois D., Wu, Dauh-Rurng, Dabros, Marta, Yang, Xiaoxia, Taylor, Tracy L., Zhou, Xia D., Heimrich, Elizabeth M., Thomas, Rochelle, McIntyre, Kim W., Shi, Hong, Levesque, Paul C., Sun, Huadong, Yang, Zheng, Marino, Anthony M., Cornelius, Georgia, D'Arienzo, Celia J., Gupta, Anuradha, Pragalathan, Bala, Rampulla, Richard, Mathur, Arvind, Shen, Ding Ren, Cvijic, Mary Ellen, Salter-Cid, Luisa, Lombardo, Louis J., Carter, Percy H., Dyckman, Alaric J.
Publicado no Medchemcomm (2016)

Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors

Por Gavai, Ashvinikumar V., Quesnelle, Claude, Norris, Derek, Han, Wen-Ching, Gill, Patrice, Shan, Weifang, Balog, Aaron, Chen, Ke, Tebben, Andrew, Rampulla, Richard, Wu, Dauh-Rurng, Zhang, Yingru, Mathur, Arvind, White, Ronald, Rose, Anne, Wang, Haiqing, Yang, Zheng, Ranasinghe, Asoka, D’Arienzo, Celia, Guarino, Victor, Xiao, Lan, Su, Ching, Everlof, Gerry, Arora, Vinod, Shen, Ding Ren, Cvijic, Mary Ellen, Menard, Krista, Wen, Mei-Li, Meredith, Jere, Trainor, George, Lombardo, Louis J., Olson, Richard, Baran, Phil S., Hunt, John T., Vite, Gregory D., Fischer, Bruce S., Westhouse, Richard A., Lee, Francis Y.
Publicado no ACS Med Chem Lett (2015)

Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK

Por Srivastava, Anurag S., Ko, Soo, Watterson, Scott H., Pattoli, Mark A., Skala, Stacey, Cheng, Lihong, Obermeier, Mary T., Vickery, Rodney, Discenza, Lorell N., D’Arienzo, Celia J., Gillooly, Kathleen M., Taylor, Tracy L., Pulicicchio, Claudine, McIntyre, Kim W., Yip, Shiuhang, Li, Peng, Sun, Dawn, Wu, Dauh-Rurng, Dai, Jun, Wang, Chunlei, Zhang, Yingru, Wang, Bei, Pawluczyk, Joseph, Kempson, James, Zhao, Rulin, Hou, Xiaoping, Rampulla, Richard, Mathur, Arvind, Galella, Michael A., Salter-Cid, Luisa, Barrish, Joel C., Carter, Percy H., Fura, Aberra, Burke, James R., Tino, Joseph A.
Publicado no ACS Med Chem Lett (2020)