Using yeast surface display to engineer a soluble and crystallizable construct of hematopoietic progenitor kinase 1 (HPK1)

le Lau, Wai L., Pearce, Bradley, Malakian, Heather, Rodrigo, Iyoncy, Xie, Dianlin, Gao, Mian, Marsilio, Frank, Chang, Chiehying, Ruzanov, Max, Muckelbauer, Jodi K., Newitt, John A., Lipovšek, Daša, Sheriff, Steven
Foilsithe in Acta Crystallogr F Struct Biol Commun (2020)

Involvement of DPP-IV catalytic residues in enzyme–saxagliptin complex formation

le Metzler, William J., Yanchunas, Joseph, Weigelt, Carolyn, Kish, Kevin, Klei, Herbert E., Xie, Dianlin, Zhang, Yaqun, Corbett, Martin, Tamura, James K., He, Bin, Hamann, Lawrence G., Kirby, Mark S., Marcinkeviciene, Jovita
Foilsithe 2008

The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor

le Kiefer, Susan E., Chang, ChiehYing J., Kimura, S. Roy, Gao, Mian, Xie, Dianlin, Zhang, Yaqun, Zhang, Guifen, Gill, Martin B., Mastalerz, Harold, Thompson, Lorin A., Cacace, Angela M., Sheriff, Steven
Foilsithe 2014

Structural and functional characterization of CFE88: Evidence that a conserved and essential bacterial protein is a methyltransferase

le Constantine, Keith L., Krystek, Stanley R., Healy, Matthew D., Doyle, Michael L., Siemers, Nathan O., Thanassi, Jane, Yan, Ning, Xie, Dianlin, Goldfarb, Valentina, Yanchunas, Joseph, Tao, Li, Dougherty, Brian A., Farmer, Bennett T.
Foilsithe 2005

The influence of adnectin binding on the extracellular domain of epidermal growth factor receptor

le Iacob, Roxana E., Chen, Guodong, Ahn, Joomi, Houel, Stephane, Wei, Hui, Mo, Jingjie, Tao, Li, Cohen, Daniel, Xie, Dianlin, Lin, Zheng, Morin, Paul E., Doyle, Michael L., Tymiak, Adrienne A., Engen, John R.
Foilsithe in J Am Soc Mass Spectrom (2014)

Discovery of Pyridazinone and Pyrazolo[1,5-a]pyridine Inhibitors of C-Terminal Src Kinase

le O’Malley, Daniel P., Ahuja, Vijay, Fink, Brian, Cao, Carolyn, Wang, Cindy, Swanson, Jesse, Wee, Susan, Gavai, Ashvinikumar V., Tokarski, John, Critton, David, Paiva, Anthony A., Johnson, Benjamin M., Szapiel, Nicolas, Xie, Dianlin
Foilsithe in ACS Med Chem Lett (2019)

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain

le Tokarski, John S., Zupa-Fernandez, Adriana, Tredup, Jeffrey A., Pike, Kristen, Chang, ChiehYing, Xie, Dianlin, Cheng, Lihong, Pedicord, Donna, Muckelbauer, Jodi, Johnson, Stephen R., Wu, Sophie, Edavettal, Suzanne C., Hong, Yang, Witmer, Mark R., Elkin, Lisa L., Blat, Yuval, Pitts, William J., Weinstein, David S., Burke, James R.
Foilsithe in J Biol Chem (2015)

Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors

le Liu, Chunjian, Lin, James, Moslin, Ryan, Tokarski, John S., Muckelbauer, Jodi, Chang, ChiehYing, Tredup, Jeffrey, Xie, Dianlin, Park, Hyunsoo, Li, Peng, Wu, Dauh-Rurng, Strnad, Joann, Zupa-Fernandez, Adriana, Cheng, Lihong, Chaudhry, Charu, Chen, Jing, Chen, Cliff, Sun, Huadong, Elzinga, Paul, D’arienzo, Celia, Gillooly, Kathleen, Taylor, Tracy L., McIntyre, Kim W., Salter-Cid, Luisa, Lombardo, Louis J., Carter, Percy H., Aranibar, Nelly, Burke, James R., Weinstein, David S.
Foilsithe in ACS Med Chem Lett (2019)

Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis

le Nair, Satheesh, Kumar, Sreekantha Ratna, Paidi, Venkatram Reddy, Sistla, Ramesh, Kantheti, Durgarao, Polimera, Subba Rao, Thangavel, Soodamani, Mukherjee, Amrita Jha, Das, Mitalee, Bhide, Rajeev S., Pitts, William J., Murugesan, Natesan, Dudhgoankar, Shailesh, Nagar, Jignesh, Subramani, Siva, Mazumder, Debarati, Carman, Julie A., Holloway, Deborah A., Li, Xin, Fereshteh, Mark P., Ruepp, Stefan, Palanisamy, Kamalavenkatesh, Mariappan, T. Thanga, Maddi, Srinivas, Saxena, Ajay, Elzinga, Paul, Chimalakonda, Anjaneya, Ruan, Qian, Ghosh, Kaushik, Bose, Sucharita, Sack, John, Yan, Chunhong, Kiefer, Susan E., Xie, Dianlin, Newitt, John A., Saravanakumar, S. Pon, Rampulla, Richard A., Barrish, Joel C., Carter, Percy H., Hynes, John
Foilsithe in ACS Med Chem Lett (2020)