Discovery of anticancer agents of diverse natural origin

Por Kinghorn, A. Douglas, Carcache de Blanco, Esperanza J., Chai, Hee-Byung, Orjala, Jimmy, Farnsworth, Norman R., Soejarto, D. Doel, Oberlies, Nicholas H., Wani, Mansukh C., Kroll, David J., Pearce, Cedric J., Swanson, Steven M., Kramer, Robert A., Rose, William C., Fairchild, Craig R., Vite, Gregory D., Emanuel, Stuart, Jarjoura, David, Cope, Frederick O.
Publicado em 2009

Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer

Por Balog, Aaron, Rampulla, Richard, Martin, Gregory S., Krystek, Stanley R., Attar, Ricardo, Dell-John, Janet, DiMarco, John D., Fairfax, David, Gougoutas, Jack, Holst, Christian L., Nation, Andrew, Rizzo, Cheryl, Rossiter, Lana M., Schweizer, Liang, Shan, Weifang, Spergel, Steven, Spires, Thomas, Cornelius, Georgia, Gottardis, Marco, Trainor, George, Vite, Gregory D., Salvati, Mark E.
Publicado no ACS Med Chem Lett (2015)

Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer

Por Zhang, Yong, Seigal, Benjamin A., Terrett, Nicholas K., Talbott, Randy L., Fargnoli, Joseph, Naglich, Joseph G., Chaudhry, Charu, Posy, Shana L., Vuppugalla, Ragini, Cornelius, Georgia, Lei, Ming, Wang, Chunlei, Zhang, Yingru, Schmidt, Robert J., Wei, Donna D., Miller, Michael M., Allen, Martin P., Li, Ling, Carter, Percy H., Vite, Gregory D., Borzilleri, Robert M.
Publicado no ACS Med Chem Lett (2015)

Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer

Por Huang, Audris, Jayaraman, Lata, Fura, Aberra, Vite, Gregory D., Trainor, George L., Gottardis, Marco M., Spires, Thomas E., Spires, Vanessa M., Rizzo, Cheryl A., Obermeier, Mary T., Elzinga, Paul A., Todderud, Gordon, Fan, Yi, Newitt, John A., Beyer, Sophie M., Zhu, Yongxin, Warrack, Bethanne M., Goodenough, Angela K., Tebben, Andrew J., Doweyko, Arthur M., Gold, David L., Balog, Aaron
Publicado no ACS Med Chem Lett (2015)

Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors

Por Gavai, Ashvinikumar V., Quesnelle, Claude, Norris, Derek, Han, Wen-Ching, Gill, Patrice, Shan, Weifang, Balog, Aaron, Chen, Ke, Tebben, Andrew, Rampulla, Richard, Wu, Dauh-Rurng, Zhang, Yingru, Mathur, Arvind, White, Ronald, Rose, Anne, Wang, Haiqing, Yang, Zheng, Ranasinghe, Asoka, D’Arienzo, Celia, Guarino, Victor, Xiao, Lan, Su, Ching, Everlof, Gerry, Arora, Vinod, Shen, Ding Ren, Cvijic, Mary Ellen, Menard, Krista, Wen, Mei-Li, Meredith, Jere, Trainor, George, Lombardo, Louis J., Olson, Richard, Baran, Phil S., Hunt, John T., Vite, Gregory D., Fischer, Bruce S., Westhouse, Richard A., Lee, Francis Y.
Publicado no ACS Med Chem Lett (2015)