Regulated Expression of the Escherichia coli lepB Gene as a Tool for Cellular Testing of Antimicrobial Compounds That Inhibit Signal Peptidase I In Vitro

por Barbosa, Maria D. F. S., Lin, Siqi, Markwalder, Jay A., Mills, Jonathan A., DeVito, Joseph A., Teleha, Christopher A., Garlapati, Vasudha, Liu, Charles, Thompson, Andy, Trainor, George L., Kurilla, Michael G., Pompliano, David L.
Publicado 2002

Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1

por Corbett, Jeffrey W., Ko, Soo S., Rodgers, James D., Jeffrey, Susan, Bacheler, Lee T., Klabe, Ronald M., Diamond, Sharon, Lai, Chii-Ming, Rabel, Shelley R., Saye, Jo Anne, Adams, Stephen P., Trainor, George L., Anderson, Paul S., Erickson-Viitanen, Susan K.
Publicado 1999

Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors

por Hart, Amy C., Schroeder, Gretchen M., Wan, Honghe, Grebinski, James, Inghrim, Jennifer, Kempson, James, Guo, Junqing, Pitts, William J., Tokarski, John S., Sack, John S., Khan, Javed A., Lippy, Jonathan, Lorenzi, Matthew V., You, Dan, McDevitt, Theresa, Vuppugalla, Ragini, Zhang, Yueping, Lombardo, Louis J., Trainor, George L., Purandare, Ashok V.
Publicado en ACS Med Chem Lett (2015)

Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer

por Huang, Audris, Jayaraman, Lata, Fura, Aberra, Vite, Gregory D., Trainor, George L., Gottardis, Marco M., Spires, Thomas E., Spires, Vanessa M., Rizzo, Cheryl A., Obermeier, Mary T., Elzinga, Paul A., Todderud, Gordon, Fan, Yi, Newitt, John A., Beyer, Sophie M., Zhu, Yongxin, Warrack, Bethanne M., Goodenough, Angela K., Tebben, Andrew J., Doweyko, Arthur M., Gold, David L., Balog, Aaron
Publicado en ACS Med Chem Lett (2015)

Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms

por Wan, Honghe, Schroeder, Gretchen M., Hart, Amy C., Inghrim, Jennifer, Grebinski, James, Tokarski, John S., Lorenzi, Matthew V., You, Dan, Mcdevitt, Theresa, Penhallow, Becky, Vuppugalla, Ragini, Zhang, Yueping, Gu, Xiaomei, Iyer, Ramaswamy, Lombardo, Louis J., Trainor, George L., Ruepp, Stefan, Lippy, Jonathan, Blat, Yuval, Sack, John S., Khan, Javed A., Stefanski, Kevin, Sleczka, Bogdan, Mathur, Arvind, Sun, Jung-Hui, Wong, Michael K., Wu, Dauh-Rurng, Li, Peng, Gupta, Anuradha, Arunachalam, P. N., Pragalathan, Bala, Narayanan, Sankara, K.C., Nanjundaswamy, Kuppusamy, Prakasam, Purandare, Ashok V.
Publicado en ACS Med Chem Lett (2015)