Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis

Bằng Liu, Qingjie, Xiao, Hai-Yun, Batt, Douglas G., Xiao, Zili, Zhu, Yeheng, Yang, Michael G., Li, Ning, Yip, Shiuhang, Li, Peng, Sun, Dawn, Wu, Dauh-Rurng, Ruzanov, Max, Sack, John S., Weigelt, Carolyn A., Wang, Jinhong, Li, Sha, Shuster, David J., Xie, Jenny H., Song, Yunling, Sherry, Tara, Obermeier, Mary T., Fura, Aberra, Stefanski, Kevin, Cornelius, Georgia, Chacko, Silvi, Khandelwal, Purnima, Dudhgaonkar, Shailesh, Rudra, Anjuman, Nagar, Jignesh, Murali, Venkata, Govindarajan, Arun, Denton, Rex, Zhao, Qihong, Meanwell, Nicholas A., Borzilleri, Robert, Dhar, T. G. Murali
Xuất bản năm ACS Med Chem Lett (2021)

Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK

Bằng Srivastava, Anurag S., Ko, Soo, Watterson, Scott H., Pattoli, Mark A., Skala, Stacey, Cheng, Lihong, Obermeier, Mary T., Vickery, Rodney, Discenza, Lorell N., D’Arienzo, Celia J., Gillooly, Kathleen M., Taylor, Tracy L., Pulicicchio, Claudine, McIntyre, Kim W., Yip, Shiuhang, Li, Peng, Sun, Dawn, Wu, Dauh-Rurng, Dai, Jun, Wang, Chunlei, Zhang, Yingru, Wang, Bei, Pawluczyk, Joseph, Kempson, James, Zhao, Rulin, Hou, Xiaoping, Rampulla, Richard, Mathur, Arvind, Galella, Michael A., Salter-Cid, Luisa, Barrish, Joel C., Carter, Percy H., Fura, Aberra, Burke, James R., Tino, Joseph A.
Xuất bản năm ACS Med Chem Lett (2020)