Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

по Galehdar, Zohreh, Swan, Patrick, Fuerth, Benjamin, Callaghan, Steven M., Park, David S., Cregan, Sean P.
Опубликовано в: J Neurosci (2010)

The JNK- and AKT/GSK3β- Signaling Pathways Converge to Regulate Puma Induction and Neuronal Apoptosis Induced by Trophic Factor Deprivation

по Ambacher, Kristin K., Pitzul, Kristen B., Karajgikar, Meera, Hamilton, Alison, Ferguson, Stephen S., Cregan, Sean P.
Опубликовано 2012

Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease

по Hamilton, Alison, Esseltine, Jessica L, DeVries, Rebecca A, Cregan, Sean P, Ferguson, Stephen S G
Опубликовано 2014

Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis

по Paquet, Maryse, Ribeiro, Fabiola M, Guadagno, Jennifer, Esseltine, Jessica L, Ferguson, Stephen SG, Cregan, Sean P
Опубликовано 2013

Activating transcription factor-4 promotes neuronal death induced by Parkinson’s disease neurotoxins and α-synuclein aggregates

по Demmings, Matthew D., Tennyson, Elizabeth C., Petroff, Gillian N., Tarnowski-Garner, Heather E., Cregan, Sean P.
Опубликовано в: Cell Death Differ (2020)

Metabotropic Glutamate Receptor-Mediated Cell Signaling Pathways Are Altered in a Mouse Model of Huntington's Disease

по Ribeiro, Fabiola M., Paquet, Maryse, Ferreira, Lucimar T., Cregan, Tamara, Swan, Patrick, Cregan, Sean P., Ferguson, Stephen S. G.
Опубликовано в: J Neurosci (2010)

Nuclear Factor-κB Modulates the p53 Response in Neurons Exposed to DNA Damage

по Aleyasin, Hossein, Cregan, Sean P., Iyirhiaro, Grace, O'Hare, Michael J., Callaghan, Steve M., Slack, Ruth S., Park, David S.
Опубликовано в: J Neurosci (2004)

Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons

по Cregan, Sean P., MacLaurin, Jason G., Craig, Constance G., Robertson, George S., Nicholson, Donald W., Park, David S., Slack, Ruth S.
Опубликовано в: J Neurosci (1999)

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

по Tang, Weihao, Tam, Joshua H.K., Seah, Claudia, Chiu, Justin, Tyrer, Andrea, Cregan, Sean P., Meakin, Susan O., Pasternak, Stephen H.
Опубликовано в: Mol Brain (2015)

Sertad1 Plays an Essential Role in Developmentaland Pathological Neuron Death

по Biswas, Subhas C., Zhang, Yi, Iyirhiaro, Grace, Willett, Ryan T., Rodriguez Gonzalez, Yasmilde, Cregan, Sean P., Slack, Ruth S., Park, David S., Greene, Lloyd A.
Опубликовано 2010

Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway

по Lorenzen, Angela, Samosh, Jonathan, Vandewark, Kenneth, Anborgh, Pieter H, Seah, Claudia, Magalhaes, Ana C, Cregan, Sean P, Ferguson, Stephen SG, Pasternak, Stephen H
Опубликовано 2010

Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

по Baxter, Paul S., Bell, Karen F.S., Hasel, Philip, Kaindl, Angela M., Fricker, Michael, Thomson, Derek, Cregan, Sean P., Gillingwater, Thomas H., Hardingham, Giles E.
Опубликовано в: Nat Commun (2015)

Corrigendum: Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

по Baxter, Paul S., Bell, Karen F. S., Hasel, Philip, Kaindl, Angela M., Fricker, Michael, Thomson, Derek., Cregan, Sean P., Gillingwater, Thomas H., Hardingham, Giles E.
Опубликовано в: Nat Commun (2017)

Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity

по Di Sebastiano, Andrea R., Fahim, Sandra, Dunn, Henry A., Walther, Cornelia, Ribeiro, Fabiola M., Cregan, Sean P., Angers, Stephane, Schmid, Susanne, Ferguson, Stephen S. G.
Опубликовано в: J Biol Chem (2016)

Puma Is a Dominant Regulator of Oxidative Stress Induced Bax Activation and Neuronal Apoptosis

по Steckley, Diana, Karajgikar, Meera, Dale, Lianne B., Fuerth, Ben, Swan, Patrick, Drummond-Main, Chris, Poulter, Michael O., Ferguson, Stephen S. G., Strasser, Andreas, Cregan, Sean P.
Опубликовано в: J Neurosci (2007)

p53 Activation Domain 1 Is Essential for PUMA Upregulation and p53-Mediated Neuronal Cell Death

по Cregan, Sean P., Arbour, Nicole A., MacLaurin, Jason G., Callaghan, Steven M., Fortin, Andre, Cheung, Eric C. C., Guberman, Daniel S., Park, David S., Slack, Ruth S.
Опубликовано в: J Neurosci (2004)

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival

по Khacho, Mireille, Tarabay, Michelle, Patten, David, Khacho, Pamela, MacLaurin, Jason G., Guadagno, Jennifer, Bergeron, Richard, Cregan, Sean P., Harper, Mary-Ellen, Park, David S., Slack, Ruth S.
Опубликовано 2014

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death

по Fortin, Andre, Cregan, Sean P., MacLaurin, Jason G., Kushwaha, Neena, Hickman, Emma S., Thompson, Charlie S., Hakim, Antoine, Albert, Paul R., Cecconi, Francesco, Helin, Kristian, Park, David S., Slack, Ruth S.
Опубликовано 2001

Apoptosis-Inducing Factor Is a Key Factor in Neuronal Cell Death Propagated by BAX-Dependent and BAX-Independent Mechanisms

по Cheung, Eric C. C., Melanson-Drapeau, Lysanne, Cregan, Sean P., Vanderluit, Jacqueline L., Ferguson, Kerry L., McIntosh, William C., Park, David S., Bennett, Steffany A. L., Slack, Ruth S.
Опубликовано в: J Neurosci (2005)

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

по Cregan, Sean P., Fortin, Andre, MacLaurin, Jason G., Callaghan, Steven M., Cecconi, Francesco, Yu, Seong-Woon, Dawson, Ted M., Dawson, Valina L., Park, David S., Kroemer, Guido, Slack, Ruth S.
Опубликовано 2002