Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

An increasing body of evidence points to a key role of endoplasmic reticulum (ER) stress in acute and chronic neurodegenerative conditions. Extensive ER stress can trigger neuronal apoptosis, but the signaling pathways that regulate this cell death remain unclear. In the present study, we demonstrat...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Galehdar, Zohreh, Swan, Patrick, Fuerth, Benjamin, Callaghan, Steven M., Park, David S., Cregan, Sean P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634926/
https://ncbi.nlm.nih.gov/pubmed/21159964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1598-10.2010
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