APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death

p53 is a transcriptional activator which has been implicated as a key regulator of neuronal cell death after acute injury. We have shown previously that p53-mediated neuronal cell death involves a Bax-dependent activation of caspase 3; however, the transcriptional targets involved in the regulation...

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Detalhes bibliográficos
Main Authors: Fortin, Andre, Cregan, Sean P., MacLaurin, Jason G., Kushwaha, Neena, Hickman, Emma S., Thompson, Charlie S., Hakim, Antoine, Albert, Paul R., Cecconi, Francesco, Helin, Kristian, Park, David S., Slack, Ruth S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198828/
https://ncbi.nlm.nih.gov/pubmed/11591730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105137
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