Case Report of a 63-Year-Old Patient With Alzheimer Disease and a Novel Presenilin 2 Mutation

por Wells, Jennie L., Pasternak, Stephen H.
Publicado no Alzheimer Dis Assoc Disord (2019)

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP

por Tam, Joshua H. K., Pasternak, Stephen H.
Publicado no J Vis Exp (2015)

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid

por Tam, Joshua HK, Seah, Claudia, Pasternak, Stephen H
Publicado no Mol Brain (2014)

Amino-Terminal β-Amyloid Antibody Blocks β-Amyloid-Mediated Inhibition of the High-Affinity Choline Transporter CHT

por Cuddy, Leah K., Seah, Claudia, Pasternak, Stephen H., Rylett, R. Jane
Publicado no Front Mol Neurosci (2017)

Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway

por Tam, Joshua H. K., Cobb, M. Rebecca, Seah, Claudia, Pasternak, Stephen H.
Publicado no PLoS One (2016)

Neuropathology of Perry Syndrome: Evidence of Medullary and Hypothalamic Involvement

por Kim, David Dongkyung, Alghefari, Huda, Jenkins, Mary, Ang, Lee‐Cyn, Pasternak, Stephen H.
Publicado no Mov Disord Clin Pract (2021)

Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates

por Roseborough, Austyn D., Langdon, Kristopher D., Hammond, Robert, Cipriano, Lauren E., Pasternak, Stephen H., Whitehead, Shawn N., Khan, Ali R.
Publicado no Neuroimage Clin (2020)

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

por Tang, Weihao, Tam, Joshua H.K., Seah, Claudia, Chiu, Justin, Tyrer, Andrea, Cregan, Sean P., Meakin, Susan O., Pasternak, Stephen H.
Publicado no Mol Brain (2015)

Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells

por Li, Chunhui, MacDonald, James I. S., Talebian, Asghar, Leuenberger, Jennifer, Seah, Claudia, Pasternak, Stephen H., Michnick, Stephen W., Meakin, Susan O.
Publicado no Mol Cell Biol (2016)

Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway

por Lorenzen, Angela, Samosh, Jonathan, Vandewark, Kenneth, Anborgh, Pieter H, Seah, Claudia, Magalhaes, Ana C, Cregan, Sean P, Ferguson, Stephen SG, Pasternak, Stephen H
Publicado em 2010

Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease

por Lackie, Rachel E., Marques-Lopes, Jose, Ostapchenko, Valeriy G., Good, Sarah, Choy, Wing-Yiu, van Oosten-Hawle, Patricija, Pasternak, Stephen H., Prado, Vania F., Prado, Marco A. M.
Publicado no Acta Neuropathol Commun (2020)

MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures

por Caetano, Fabiana A., Dirk, Brennan S., Tam, Joshua H. K., Cavanagh, P. Craig, Goiko, Maria, Ferguson, Stephen S. G., Pasternak, Stephen H., Dikeakos, Jimmy D., de Bruyn, John R., Heit, Bryan
Publicado no PLoS Comput Biol (2015)

Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer's Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [(68)Ga]Ga-TC3-OGDOTA

por Ostapchenko, Valeriy G., Snir, Jonatan, Suchy, Mojmir, Fan, Jue, Cobb, M. Rebecca, Chronik, Blaine A., Kovacs, Michael, Prado, Vania F., Hudson, Robert H. E., Pasternak, Stephen H., Prado, Marco A. M., Bartha, Robert
Publicado no Contrast Media Mol Imaging (2019)

Structural Brain Magnetic Resonance Imaging to Rule Out Comorbid Pathology in the Assessment of Alzheimer’s Disease Dementia: Findings from the Ontario Neurodegenerative Disease Re...

por Kapoor, Arunima, Bartha, Robert, Black, Sandra E., Borrie, Michael, Freedman, Morris, Gao, Fuqiang, Herrmann, Nathan, Mandzia, Jennifer, Ozzoude, Miracle, Ramirez, Joel, Scott, Christopher J.M., Symons, Sean, Fischer, Corinne E., Frank, Andrew, Seitz, Dallas, Wolf, Michael Uri, Verhoeff, Nicolaas Paul L.G., Naglie, Gary, Reichman, William, Masellis, Mario, Mitchell, Sara B., Tang-Wai, David F., Tartaglia, Maria Carmela, Kumar, Sanjeev, Pollock, Bruce G., Rajji, Tarek K., Finger, Elizabeth, Pasternak, Stephen H., Swartz, Richard H.
Publicado no J Alzheimers Dis (2020)