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The JNK- and AKT/GSK3β- Signaling Pathways Converge to Regulate Puma Induction and Neuronal Apoptosis Induced by Trophic Factor Deprivation

The AKT, GSK3 and JNK family kinases have been implicated in neuronal apoptosis associated with neuronal development and several neurodegenerative conditions. However, the mechanisms by which these kinase pathways regulate apoptosis remain unclear. In this study we have investigated the role of thes...

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Detalhes bibliográficos
Principais autores: Ambacher, Kristin K., Pitzul, Kristen B., Karajgikar, Meera, Hamilton, Alison, Ferguson, Stephen S., Cregan, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463558/
https://ncbi.nlm.nih.gov/pubmed/23056511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046885
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