JNK1-dependent PUMA Expression Contributes to Hepatocyte Lipoapoptosis

Free fatty acids (FFA) induce hepatocyte lipoapoptosis by a c-Jun N-terminal kinase (JNK)-dependent mechanism. However, the cellular processes by which JNK engages the core apoptotic machinery during lipotoxicity, especially activation of BH3-only proteins, remain incompletely understood. Thus, our...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cazanave, Sophie C., Mott, Justin L., Elmi, Nafisa A., Bronk, Steven F., Werneburg, Nathan W., Akazawa, Yuko, Kahraman, Alisan, Garrison, Sean P., Zambetti, Gerard P., Charlton, Michael R., Gores, Gregory J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Mechanisms of Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785347/
https://ncbi.nlm.nih.gov/pubmed/19638343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022491
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