CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis

Endoplasmic reticulum (ER) stress-mediated apoptosis is a key feature of hepatocyte cytotoxicity by saturated free fatty acids (FFA). This lipoapoptosis is dependent, in part, on the transcriptional upregulation of the BH3-only protein PUMA (p53 upregulated modulator of apoptosis). Although the acti...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Cazanave, Sophie C., Elmi, Nafisa A., Akazawa, Yuko, Bronk, Steven F., Mott, Justin L., Gores, Gregory J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Liver and Biliary Tract
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904106/
https://ncbi.nlm.nih.gov/pubmed/20430872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00091.2010
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki