Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity

Activation of Group I metabotropic glutamate receptors (mGluRs) activates signaling cascades, resulting in calcium release from intracellular stores, ERK1/2 activation, and long term changes in synaptic activity that are implicated in learning, memory, and neurodegenerative diseases. As such, elucid...

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Vydáno v:J Biol Chem
Hlavní autoři: Di Sebastiano, Andrea R., Fahim, Sandra, Dunn, Henry A., Walther, Cornelia, Ribeiro, Fabiola M., Cregan, Sean P., Angers, Stephane, Schmid, Susanne, Ferguson, Stephen S. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016157/
https://ncbi.nlm.nih.gov/pubmed/27358397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722355
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