Ca(2+)/Calmodulin-dependent protein Kinase II interacts with group I Metabotropic Glutamate and facilitates Receptor Endocytosis and ERK1/2 signaling: role of β-Amyloid

BACKGROUND: Agonist stimulation of Group I metabotropic glutamate receptors (mGluRs) initiates their coupling to the heterotrimeric G protein, Gα(q/11), resulting in the activation of phospholipase C, the release of Ca(2+) from intracellular stores and the subsequent activation of protein kinase C....

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Vydáno v:Mol Brain
Hlavní autoři: Raka, Fitore, Di Sebastiano, Andrea R, Kulhawy, Stephanie C, Ribeiro, Fabiola M, Godin, Christina M, Caetano, Fabiana A, Angers, Stephane, Ferguson, Stephen S G
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378271/
https://ncbi.nlm.nih.gov/pubmed/25885040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0111-4
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