Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

von Galehdar, Zohreh, Swan, Patrick, Fuerth, Benjamin, Callaghan, Steven M., Park, David S., Cregan, Sean P.
Veröffentlicht in J Neurosci (2010)

The JNK- and AKT/GSK3β- Signaling Pathways Converge to Regulate Puma Induction and Neuronal Apoptosis Induced by Trophic Factor Deprivation

von Ambacher, Kristin K., Pitzul, Kristen B., Karajgikar, Meera, Hamilton, Alison, Ferguson, Stephen S., Cregan, Sean P.
Veröffentlicht 2012

Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease

von Hamilton, Alison, Esseltine, Jessica L, DeVries, Rebecca A, Cregan, Sean P, Ferguson, Stephen S G
Veröffentlicht 2014

Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis

von Paquet, Maryse, Ribeiro, Fabiola M, Guadagno, Jennifer, Esseltine, Jessica L, Ferguson, Stephen SG, Cregan, Sean P
Veröffentlicht 2013

Activating transcription factor-4 promotes neuronal death induced by Parkinson’s disease neurotoxins and α-synuclein aggregates

von Demmings, Matthew D., Tennyson, Elizabeth C., Petroff, Gillian N., Tarnowski-Garner, Heather E., Cregan, Sean P.
Veröffentlicht in Cell Death Differ (2020)

Metabotropic Glutamate Receptor-Mediated Cell Signaling Pathways Are Altered in a Mouse Model of Huntington's Disease

von Ribeiro, Fabiola M., Paquet, Maryse, Ferreira, Lucimar T., Cregan, Tamara, Swan, Patrick, Cregan, Sean P., Ferguson, Stephen S. G.
Veröffentlicht in J Neurosci (2010)

Nuclear Factor-κB Modulates the p53 Response in Neurons Exposed to DNA Damage

von Aleyasin, Hossein, Cregan, Sean P., Iyirhiaro, Grace, O'Hare, Michael J., Callaghan, Steve M., Slack, Ruth S., Park, David S.
Veröffentlicht in J Neurosci (2004)

Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons

von Cregan, Sean P., MacLaurin, Jason G., Craig, Constance G., Robertson, George S., Nicholson, Donald W., Park, David S., Slack, Ruth S.
Veröffentlicht in J Neurosci (1999)

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

von Tang, Weihao, Tam, Joshua H.K., Seah, Claudia, Chiu, Justin, Tyrer, Andrea, Cregan, Sean P., Meakin, Susan O., Pasternak, Stephen H.
Veröffentlicht in Mol Brain (2015)

Sertad1 Plays an Essential Role in Developmentaland Pathological Neuron Death

von Biswas, Subhas C., Zhang, Yi, Iyirhiaro, Grace, Willett, Ryan T., Rodriguez Gonzalez, Yasmilde, Cregan, Sean P., Slack, Ruth S., Park, David S., Greene, Lloyd A.
Veröffentlicht 2010

Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway

von Lorenzen, Angela, Samosh, Jonathan, Vandewark, Kenneth, Anborgh, Pieter H, Seah, Claudia, Magalhaes, Ana C, Cregan, Sean P, Ferguson, Stephen SG, Pasternak, Stephen H
Veröffentlicht 2010

Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

von Baxter, Paul S., Bell, Karen F.S., Hasel, Philip, Kaindl, Angela M., Fricker, Michael, Thomson, Derek, Cregan, Sean P., Gillingwater, Thomas H., Hardingham, Giles E.
Veröffentlicht in Nat Commun (2015)

Corrigendum: Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

von Baxter, Paul S., Bell, Karen F. S., Hasel, Philip, Kaindl, Angela M., Fricker, Michael, Thomson, Derek., Cregan, Sean P., Gillingwater, Thomas H., Hardingham, Giles E.
Veröffentlicht in Nat Commun (2017)

Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity

von Di Sebastiano, Andrea R., Fahim, Sandra, Dunn, Henry A., Walther, Cornelia, Ribeiro, Fabiola M., Cregan, Sean P., Angers, Stephane, Schmid, Susanne, Ferguson, Stephen S. G.
Veröffentlicht in J Biol Chem (2016)

Puma Is a Dominant Regulator of Oxidative Stress Induced Bax Activation and Neuronal Apoptosis

von Steckley, Diana, Karajgikar, Meera, Dale, Lianne B., Fuerth, Ben, Swan, Patrick, Drummond-Main, Chris, Poulter, Michael O., Ferguson, Stephen S. G., Strasser, Andreas, Cregan, Sean P.
Veröffentlicht in J Neurosci (2007)

p53 Activation Domain 1 Is Essential for PUMA Upregulation and p53-Mediated Neuronal Cell Death

von Cregan, Sean P., Arbour, Nicole A., MacLaurin, Jason G., Callaghan, Steven M., Fortin, Andre, Cheung, Eric C. C., Guberman, Daniel S., Park, David S., Slack, Ruth S.
Veröffentlicht in J Neurosci (2004)

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival

von Khacho, Mireille, Tarabay, Michelle, Patten, David, Khacho, Pamela, MacLaurin, Jason G., Guadagno, Jennifer, Bergeron, Richard, Cregan, Sean P., Harper, Mary-Ellen, Park, David S., Slack, Ruth S.
Veröffentlicht 2014

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death

von Fortin, Andre, Cregan, Sean P., MacLaurin, Jason G., Kushwaha, Neena, Hickman, Emma S., Thompson, Charlie S., Hakim, Antoine, Albert, Paul R., Cecconi, Francesco, Helin, Kristian, Park, David S., Slack, Ruth S.
Veröffentlicht 2001

Apoptosis-Inducing Factor Is a Key Factor in Neuronal Cell Death Propagated by BAX-Dependent and BAX-Independent Mechanisms

von Cheung, Eric C. C., Melanson-Drapeau, Lysanne, Cregan, Sean P., Vanderluit, Jacqueline L., Ferguson, Kerry L., McIntosh, William C., Park, David S., Bennett, Steffany A. L., Slack, Ruth S.
Veröffentlicht in J Neurosci (2005)

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

von Cregan, Sean P., Fortin, Andre, MacLaurin, Jason G., Callaghan, Steven M., Cecconi, Francesco, Yu, Seong-Woon, Dawson, Ted M., Dawson, Valina L., Park, David S., Kroemer, Guido, Slack, Ruth S.
Veröffentlicht 2002