Unexpected pieces to the senescence puzzle

le Cichowski, Karen, Hahn, William C.
Foilsithe 2008

Identifying the ubiquitin ligase complex that regulates the NF1 tumor suppressor and Ras

le Hollstein, Pablo E., Cichowski, Karen
Foilsithe 2013

SPRED proteins provide a NF-ty link to Ras suppression

le McClatchey, Andrea I., Cichowski, Karen
Foilsithe 2012

Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is

le Liao, Sida, Maertens, Ophélia, Cichowski, Karen, Elledge, Stephen J.
Foilsithe in Genes Dev (2018)

Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor

le Cichowski, Karen, Santiago, Sabrina, Jardim, Melanie, Johnson, Bryan W., Jacks, Tyler
Foilsithe 2003

The NF1 tumor suppressor critically regulates TSC2 and mTOR

le Johannessen, Cory M., Reczek, Elizabeth E., James, Marianne F., Brems, Hilde, Legius, Eric, Cichowski, Karen
Foilsithe 2005

Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers

le Malone, Clare F., Fromm, Jody A., Maertens, Ophélia, DeRaedt, Thomas, Ingraham, Rachel, Cichowski, Karen
Foilsithe in Cancer Discov (2014)

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

le Johnson, Leisa, Greenbaum, Doron, Cichowski, Karen, Mercer, Kim, Murphy, Elizabeth, Schmitt, Eric, Bronson, Roderick T., Umanoff, Heywood, Edelmann, Windfried, Kucherlapati, Raju, Jacks, Tyler
Foilsithe 1997

ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

le Engelman, Jeffrey A., Jänne, Pasi A., Mermel, Craig, Pearlberg, Joseph, Mukohara, Toru, Fleet, Christina, Cichowski, Karen, Johnson, Bruce E., Cantley, Lewis C.
Foilsithe 2005

Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers

le Lock, Rebecca, Ingraham, Rachel, Maertens, Ophélia, Miller, Abigail L., Weledji, Nelly, Legius, Eric, Konicek, Bruce M., Yan, Sau-Chi B., Graff, Jeremy R., Cichowski, Karen
Foilsithe in J Clin Invest (2016)

A negative feedback signaling network underlies oncogene-induced senescence

le Courtois-Cox, Stéphanie, Genther Williams, Sybil M., Reczek, Elizabeth E., Johnson, Bryan W., McGillicuddy, Lauren T., Johannessen, Cory M., Hollstein, Pablo, MacCollin, Mia, Cichowski, Karen
Foilsithe 2006

The RasGAP Gene, RASAL2, is a Tumor and Metastasis Suppressor

le McLaughlin, Sara Koenig, Olsen, Sarah Naomi, Dake, Benjamin, De Raedt, Thomas, Lim, Elgene, Bronson, Roderick Terry, Beroukhim, Rameen, Polyak, Kornelia, Brown, Myles, Kuperwasser, Charlotte, Cichowski, Karen
Foilsithe 2013

mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors

le Malone, Clare F., Emerson, Chloe, Ingraham, Rachel, Barbosa, William, Guerra, Stephanie, Yoon, Haejin, Liu, Lin L., Michor, Franziska, Haigis, Marcia, Macleod, Kay F., Maertens, Ophélia, Cichowski, Karen
Foilsithe in Cancer Discov (2017)

Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

le Zhang, Yang, Guillermier, Christelle, De Raedt, Thomas, Cox, Andrew G., Maertens, Ophelia, Yimlamai, Dean, Lun, Mingyue, Whitney, Adam, Maas, Richard L., Goessling, Wolfram, Cichowski, Karen, Steinhauser, Matthew L.
Foilsithe in iScience (2020)

Elucidating distinct roles for NF1 in melanomagenesis

le Maertens, Ophélia, Johnson, Bryan, Hollstein, Pablo, Frederick, Dennie T., Cooper, Zachary A., Messiaen, Ludwine, Bronson, Roderick T., McMahon, Martin, Granter, Scott, Flaherty, Keith, Wargo, Jennifer A., Marais, Richard, Cichowski, Karen
Foilsithe 2012

Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

le Takahashi, Nobuaki, Chen, Hsing-Yu, Harris, Isaac S., Stover, Daniel G., Selfors, Laura M., Bronson, Roderick T., Deraedt, Thomas, Cichowski, Karen, Welm, Alana L., Mori, Yasuo, Mills, Gordon B., Brugge, Joan S.
Foilsithe in Cancer Cell (2018)

IL1α antagonizes IL1β and promotes adaptive immune rejection of malignant tumors

le Tian, Tian, Lofftus, Serena, Pan, Youdong, Stingley, Claire A, King, Sandra L, Zhao, Jingxia, Pan, Timothy Y, Lock, Rebecca, Marglous, Jacob W, Liu, Kevin, Widlund, Hans R, Fuhlbrigge, Robert, Cichowski, Karen, Kupper, Thomas S
Foilsithe in Cancer Immunol Res (2020)

Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy

le Montero, Joan, Sarosiek, Kristopher A., DeAngelo, Joseph D., Maertens, Ophélia, Ryan, Jeremy, Ercan, Dalia, Piao, Huiying, Horowitz, Neil S., Berkowitz, Ross S., Matulonis, Ursula, Jänne, Pasi A., Amrein, Philip C., Cichowski, Karen, Drapkin, Ronny, Letai, Anthony
Foilsithe in Cell (2015)

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies

le Maertens, Ophélia, McCurrach, Mila E., Braun, Benjamin S., De Raedt, Thomas, Epstein, Inbal, Huang, Tannie Q., Lauchle, Jennifer O., Lee, Hyerim, Wu, Jianqiang, Cripe, Timothy P., Clapp, D. Wade, Ratner, Nancy, Shannon, Kevin, Cichowski, Karen
Foilsithe in Cancer Res (2017)

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-κB

le Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K., Reczek, Elizabeth E., De Raedt, Thomas, Guney, Isil, Strochlic, David E., Laura, E., Beroukhim, Rameen, Bronson, Roderick T., Ryeom, Sandra, Hahn, William C., Loda, Massimo, Cichowski, Karen
Foilsithe 2010