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Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

Malignant tumors exhibit high degrees of genomic heterogeneity at the cellular level, leading to the view that subpopulations of tumor cells drive growth and treatment resistance. To examine the degree to which tumors also exhibit metabolic heterogeneity at the level of individual cells, we employed...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Zhang, Yang, Guillermier, Christelle, De Raedt, Thomas, Cox, Andrew G., Maertens, Ophelia, Yimlamai, Dean, Lun, Mingyue, Whitney, Adam, Maas, Richard L., Goessling, Wolfram, Cichowski, Karen, Steinhauser, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390776/
https://ncbi.nlm.nih.gov/pubmed/32712466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101355
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