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Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy

There is a lack of effective predictive biomarkers to precisely assign optimal therapy to cancer patients. While most efforts are directed at inferring drug response phenotype based on genotype, there is very focused and useful phenotypic information to be gained from directly perturbing the patient...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Montero, Joan, Sarosiek, Kristopher A., DeAngelo, Joseph D., Maertens, Ophélia, Ryan, Jeremy, Ercan, Dalia, Piao, Huiying, Horowitz, Neil S., Berkowitz, Ross S., Matulonis, Ursula, Jänne, Pasi A., Amrein, Philip C., Cichowski, Karen, Drapkin, Ronny, Letai, Anthony
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391197/
https://ncbi.nlm.nih.gov/pubmed/25723171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.042
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