Unexpected pieces to the senescence puzzle

অনুযায়ী Cichowski, Karen, Hahn, William C.
প্রকাশিত 2008

Identifying the ubiquitin ligase complex that regulates the NF1 tumor suppressor and Ras

অনুযায়ী Hollstein, Pablo E., Cichowski, Karen
প্রকাশিত 2013

SPRED proteins provide a NF-ty link to Ras suppression

অনুযায়ী McClatchey, Andrea I., Cichowski, Karen
প্রকাশিত 2012

Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is

অনুযায়ী Liao, Sida, Maertens, Ophélia, Cichowski, Karen, Elledge, Stephen J.
প্রকাশিত Genes Dev (2018)

Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor

অনুযায়ী Cichowski, Karen, Santiago, Sabrina, Jardim, Melanie, Johnson, Bryan W., Jacks, Tyler
প্রকাশিত 2003

The NF1 tumor suppressor critically regulates TSC2 and mTOR

অনুযায়ী Johannessen, Cory M., Reczek, Elizabeth E., James, Marianne F., Brems, Hilde, Legius, Eric, Cichowski, Karen
প্রকাশিত 2005

Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers

অনুযায়ী Malone, Clare F., Fromm, Jody A., Maertens, Ophélia, DeRaedt, Thomas, Ingraham, Rachel, Cichowski, Karen
প্রকাশিত Cancer Discov (2014)

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

অনুযায়ী Johnson, Leisa, Greenbaum, Doron, Cichowski, Karen, Mercer, Kim, Murphy, Elizabeth, Schmitt, Eric, Bronson, Roderick T., Umanoff, Heywood, Edelmann, Windfried, Kucherlapati, Raju, Jacks, Tyler
প্রকাশিত 1997

ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

অনুযায়ী Engelman, Jeffrey A., Jänne, Pasi A., Mermel, Craig, Pearlberg, Joseph, Mukohara, Toru, Fleet, Christina, Cichowski, Karen, Johnson, Bruce E., Cantley, Lewis C.
প্রকাশিত 2005

Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers

অনুযায়ী Lock, Rebecca, Ingraham, Rachel, Maertens, Ophélia, Miller, Abigail L., Weledji, Nelly, Legius, Eric, Konicek, Bruce M., Yan, Sau-Chi B., Graff, Jeremy R., Cichowski, Karen
প্রকাশিত J Clin Invest (2016)

A negative feedback signaling network underlies oncogene-induced senescence

অনুযায়ী Courtois-Cox, Stéphanie, Genther Williams, Sybil M., Reczek, Elizabeth E., Johnson, Bryan W., McGillicuddy, Lauren T., Johannessen, Cory M., Hollstein, Pablo, MacCollin, Mia, Cichowski, Karen
প্রকাশিত 2006

The RasGAP Gene, RASAL2, is a Tumor and Metastasis Suppressor

অনুযায়ী McLaughlin, Sara Koenig, Olsen, Sarah Naomi, Dake, Benjamin, De Raedt, Thomas, Lim, Elgene, Bronson, Roderick Terry, Beroukhim, Rameen, Polyak, Kornelia, Brown, Myles, Kuperwasser, Charlotte, Cichowski, Karen
প্রকাশিত 2013

mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors

অনুযায়ী Malone, Clare F., Emerson, Chloe, Ingraham, Rachel, Barbosa, William, Guerra, Stephanie, Yoon, Haejin, Liu, Lin L., Michor, Franziska, Haigis, Marcia, Macleod, Kay F., Maertens, Ophélia, Cichowski, Karen
প্রকাশিত Cancer Discov (2017)

Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

অনুযায়ী Zhang, Yang, Guillermier, Christelle, De Raedt, Thomas, Cox, Andrew G., Maertens, Ophelia, Yimlamai, Dean, Lun, Mingyue, Whitney, Adam, Maas, Richard L., Goessling, Wolfram, Cichowski, Karen, Steinhauser, Matthew L.
প্রকাশিত iScience (2020)

Elucidating distinct roles for NF1 in melanomagenesis

অনুযায়ী Maertens, Ophélia, Johnson, Bryan, Hollstein, Pablo, Frederick, Dennie T., Cooper, Zachary A., Messiaen, Ludwine, Bronson, Roderick T., McMahon, Martin, Granter, Scott, Flaherty, Keith, Wargo, Jennifer A., Marais, Richard, Cichowski, Karen
প্রকাশিত 2012

Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

অনুযায়ী Takahashi, Nobuaki, Chen, Hsing-Yu, Harris, Isaac S., Stover, Daniel G., Selfors, Laura M., Bronson, Roderick T., Deraedt, Thomas, Cichowski, Karen, Welm, Alana L., Mori, Yasuo, Mills, Gordon B., Brugge, Joan S.
প্রকাশিত Cancer Cell (2018)

IL1α antagonizes IL1β and promotes adaptive immune rejection of malignant tumors

অনুযায়ী Tian, Tian, Lofftus, Serena, Pan, Youdong, Stingley, Claire A, King, Sandra L, Zhao, Jingxia, Pan, Timothy Y, Lock, Rebecca, Marglous, Jacob W, Liu, Kevin, Widlund, Hans R, Fuhlbrigge, Robert, Cichowski, Karen, Kupper, Thomas S
প্রকাশিত Cancer Immunol Res (2020)

Drug-induced death signaling strategy rapidly predicts cancer response to chemotherapy

অনুযায়ী Montero, Joan, Sarosiek, Kristopher A., DeAngelo, Joseph D., Maertens, Ophélia, Ryan, Jeremy, Ercan, Dalia, Piao, Huiying, Horowitz, Neil S., Berkowitz, Ross S., Matulonis, Ursula, Jänne, Pasi A., Amrein, Philip C., Cichowski, Karen, Drapkin, Ronny, Letai, Anthony
প্রকাশিত Cell (2015)

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies

অনুযায়ী Maertens, Ophélia, McCurrach, Mila E., Braun, Benjamin S., De Raedt, Thomas, Epstein, Inbal, Huang, Tannie Q., Lauchle, Jennifer O., Lee, Hyerim, Wu, Jianqiang, Cripe, Timothy P., Clapp, D. Wade, Ratner, Nancy, Shannon, Kevin, Cichowski, Karen
প্রকাশিত Cancer Res (2017)

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-κB

অনুযায়ী Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K., Reczek, Elizabeth E., De Raedt, Thomas, Guney, Isil, Strochlic, David E., Laura, E., Beroukhim, Rameen, Bronson, Roderick T., Ryeom, Sandra, Hahn, William C., Loda, Massimo, Cichowski, Karen
প্রকাশিত 2010