Regulation of T cell development by c-Cbl: essential role of Lck

Por Chiang, Y. Jeffrey, Hodes, Richard J.
Publicado no Int Immunol (2015)

T cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages

Por Chiang, Y. Jeffrey, Hodes, Richard J.
Publicado no Eur J Immunol (2016)

Telomere-Associated Protein TIN2 Is Essential for Early Embryonic Development through a Telomerase-Independent Pathway

Por Chiang, Y. Jeffrey, Kim, Sahn-Ho, Tessarollo, Lino, Campisi, Judith, Hodes, Richard J.
Publicado em 2004

Exon 1 Disruption Alters Tissue-Specific Expression of Mouse p53 and Results in Selective Development of B Cell Lymphomas

Por Chiang, Y. Jeffrey, Difilippantonio, Michael J., Tessarollo, Lino, Morse, Herbert C., Hodes, Richard J.
Publicado em 2012

Telomere length is inherited with resetting of the telomere set-point

Por Chiang, Y. Jeffrey, Calado, Rodrigo T., Hathcock, Karen S., Lansdorp, Peter M., Young, Neal S., Hodes, Richard J.
Publicado em 2010

Cbl Enforces an SLP76-dependent Signaling Pathway for T Cell Differentiation

Por Chiang, Y. Jeffrey, Jordan, Martha S., Horai, Reiko, Schwartzberg, Pamela L., Koretzky, Gary A., Hodes, Richard J.
Publicado em 2009

Expression of Telomerase RNA Template, but Not Telomerase Reverse Transcriptase, Is Limiting for Telomere Length Maintenance In Vivo

Por Chiang, Y. Jeffrey, Hemann, Michael T., Hathcock, Karen S., Tessarollo, Lino, Feigenbaum, Lionel, Hahn, William C., Hodes, Richard J.
Publicado em 2004

Generation and Characterization of Telomere Length Maintenance in Tankyrase 2-Deficient Mice

Por Chiang, Y. Jeffrey, Nguyen, My-Linh, Gurunathan, Sujatha, Kaminker, Patrick, Tessarollo, Lino, Campisi, Judith, Hodes, Richard J.
Publicado em 2006

Tankyrase 1 and Tankyrase 2 Are Essential but Redundant for Mouse Embryonic Development

Por Chiang, Y. Jeffrey, Hsiao, Susan J., Yver, Dena, Cushman, Samuel W., Tessarollo, Lino, Smith, Susan, Hodes, Richard J.
Publicado em 2008

Co-stimulatory function in primary germinal center responses: CD40 and B7 are required on distinct antigen-presenting cells

Por Watanabe, Masashi, Fujihara, Chiharu, Radtke, Andrea J., Chiang, Y. Jeffrey, Bhatia, Sumeena, Germain, Ronald N., Hodes, Richard J.
Publicado no J Exp Med (2017)

Inactivation of c-Cbl Reverses Neonatal Lethality and T Cell Developmental Arrest of SLP-76–deficient Mice

Por Chiang, Y. Jeffrey, Sommers, Connie L., Jordan, Martha S., Gu, Hua, Samelson, Lawrence E., Koretzky, Gary A., Hodes, Richard J.
Publicado em 2004

Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence

Por Nakamura, Asako J, Chiang, Y Jeffrey, Hathcock, Karen S, Horikawa, Izumi, Sedelnikova, Olga A, Hodes, Richard J, Bonner, William M
Publicado em 2008

Loss of Dact1 Disrupts Planar Cell Polarity Signaling by Altering Dishevelled Activity and Leads to Posterior Malformation in Mice

Por Wen, Jun, Chiang, Y. Jeffrey, Gao, Chan, Xue, Hua, Xu, Jingyue, Ning, Yuanheng, Hodes, Richard J., Gao, Xiang, Chen, Ye-Guang
Publicado em 2010

Differential cis-regulation of human versus mouse TERT gene expression in vivo: Identification of a human-specific repressive element

Por Horikawa, Izumi, Chiang, Y. Jeffrey, Patterson, Tricia, Feigenbaum, Lionel, Leem, Sun-Hee, Michishita, Eriko, Larionov, Vladimir, Hodes, Richard J., Barrett, J. Carl
Publicado em 2005

E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation

Por Qiao, Guilin, Ying, Haiyan, Zhao, Yixia, Liang, Yanran, Guo, Hui, Shen, Huifeng, Li, Zhenping, Solway, Julian, Tao, Enxiang, Chiang, Y. Jeffrey, Lipkowitz, Stanley, Penninger, Josef M., Langdon, Wallace Y., Zhang, Jian
Publicado em 2014