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T cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages
Lck is a T cell lineage-specific tyrosine kinase critical for T cell development and activation through its role in pre-TCR and TCR signaling. Expression of identical Lck protein can be mediated by either proximal or distal lck promoter, but the function of these promoters in T cell development has...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5183457/ https://ncbi.nlm.nih.gov/pubmed/27469439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646440 |
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