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T cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages

Lck is a T cell lineage-specific tyrosine kinase critical for T cell development and activation through its role in pre-TCR and TCR signaling. Expression of identical Lck protein can be mediated by either proximal or distal lck promoter, but the function of these promoters in T cell development has...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Immunol
Egile Nagusiak: Chiang, Y. Jeffrey, Hodes, Richard J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5183457/
https://ncbi.nlm.nih.gov/pubmed/27469439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646440
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