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Regulation of T cell development by c-Cbl: essential role of Lck
A canonical pre-TCR/TCR signaling pathway critical for thymic T cell development involves sequential phosphorylation and signaling through Lck, Zap70, Lat and Slp76. However, we and others have previously reported that genomic deletion of c-Cbl (Cbl) partially or completely reverses the defects in t...
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| Published in: | Int Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406264/ https://ncbi.nlm.nih.gov/pubmed/25477210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxu105 |
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