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Negative regulation of Lck by Cbl ubiquitin ligase
The Cbl-family ubiquitin ligases function as negative regulators of activated receptor tyrosine kinases by facilitating their ubiquitination and subsequent targeting to lysosomes. Cbl associates with the lymphoid-restricted nonreceptor tyrosine kinase Lck, but the functional relevance of this intera...
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Prif Awduron: | , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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The National Academy of Sciences
2002
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Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122603/ https://ncbi.nlm.nih.gov/pubmed/11904433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062055999 |
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