Negative regulation of Lck by Cbl ubiquitin ligase

The Cbl-family ubiquitin ligases function as negative regulators of activated receptor tyrosine kinases by facilitating their ubiquitination and subsequent targeting to lysosomes. Cbl associates with the lymphoid-restricted nonreceptor tyrosine kinase Lck, but the functional relevance of this intera...

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Autors principals: Rao, Navin, Miyake, Sachiko, Reddi, Alagarsamy Lakku, Douillard, Patrice, Ghosh, Amiya K., Dodge, Ingrid L., Zhou, Pengcheng, Fernandes, Norvin D., Band, Hamid
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122603/
https://ncbi.nlm.nih.gov/pubmed/11904433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062055999
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