Expression of Telomerase RNA Template, but Not Telomerase Reverse Transcriptase, Is Limiting for Telomere Length Maintenance In Vivo

Telomerase consists of two essential components, the telomerase RNA template (TR) and telomerase reverse transcriptase (TERT). The haplo-insufficiency of TR was recently shown to cause one form of human dyskeratosis congenita, an inherited disease marked by abnormal telomere shortening. Consistent w...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Chiang, Y. Jeffrey, Hemann, Michael T., Hathcock, Karen S., Tessarollo, Lino, Feigenbaum, Lionel, Hahn, William C., Hodes, Richard J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2004
Gaiak:
DNA Dynamics and Chromosome Structure
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.7024-7031.2004
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