Expression of Telomerase RNA Template, but Not Telomerase Reverse Transcriptase, Is Limiting for Telomere Length Maintenance In Vivo

Telomerase consists of two essential components, the telomerase RNA template (TR) and telomerase reverse transcriptase (TERT). The haplo-insufficiency of TR was recently shown to cause one form of human dyskeratosis congenita, an inherited disease marked by abnormal telomere shortening. Consistent w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chiang, Y. Jeffrey, Hemann, Michael T., Hathcock, Karen S., Tessarollo, Lino, Feigenbaum, Lionel, Hahn, William C., Hodes, Richard J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2004
Pynciau:
DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC479722/
https://ncbi.nlm.nih.gov/pubmed/15282303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7024-7031.2004
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