Expression of Telomerase RNA Template, but Not Telomerase Reverse Transcriptase, Is Limiting for Telomere Length Maintenance In Vivo

Telomerase consists of two essential components, the telomerase RNA template (TR) and telomerase reverse transcriptase (TERT). The haplo-insufficiency of TR was recently shown to cause one form of human dyskeratosis congenita, an inherited disease marked by abnormal telomere shortening. Consistent w...

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Foilsithe in:	Mol Cell Biol
Príomhchruthaitheoirí:	Chiang, Y. Jeffrey, Hemann, Michael T., Hathcock, Karen S., Tessarollo, Lino, Feigenbaum, Lionel, Hahn, William C., Hodes, Richard J.
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Taylor & Francis 2004
Ábhair:	DNA Dynamics and Chromosome Structure
Rochtain ar líne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.7024-7031.2004
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