Expression of Telomerase RNA Template, but Not Telomerase Reverse Transcriptase, Is Limiting for Telomere Length Maintenance In Vivo

Telomerase consists of two essential components, the telomerase RNA template (TR) and telomerase reverse transcriptase (TERT). The haplo-insufficiency of TR was recently shown to cause one form of human dyskeratosis congenita, an inherited disease marked by abnormal telomere shortening. Consistent w...

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Detaylı Bibliyografya
Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Chiang, Y. Jeffrey, Hemann, Michael T., Hathcock, Karen S., Tessarollo, Lino, Feigenbaum, Lionel, Hahn, William C., Hodes, Richard J.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 2004
Konular:	DNA Dynamics and Chromosome Structure
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.7024-7031.2004
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Expression of Telomerase RNA Template, but Not Telomerase Reverse Transcriptase, Is Limiting for Telomere Length Maintenance In Vivo

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