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Telomere length is inherited with resetting of the telomere set-point
We have studied models of telomerase haploinsufficiency in humans and mice to analyze regulation of telomere length and the significance of “set points” in inheritance of telomere length. In three families with clinical syndromes associated with short telomeres resulting from haploinsufficient mutat...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890496/ https://ncbi.nlm.nih.gov/pubmed/20479226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913125107 |
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