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Telomere length is inherited with resetting of the telomere set-point

We have studied models of telomerase haploinsufficiency in humans and mice to analyze regulation of telomere length and the significance of “set points” in inheritance of telomere length. In three families with clinical syndromes associated with short telomeres resulting from haploinsufficient mutat...

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Detalhes bibliográficos
Main Authors: Chiang, Y. Jeffrey, Calado, Rodrigo T., Hathcock, Karen S., Lansdorp, Peter M., Young, Neal S., Hodes, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890496/
https://ncbi.nlm.nih.gov/pubmed/20479226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913125107
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