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Telomere length is reset during early mammalian embryogenesis

The enzyme telomerase is active in germ cells and early embryonic development and is crucial for the maintenance of telomere length. Whereas the different length of telomeres in germ cells and somatic cells is well documented, information on telomere length regulation during embryogenesis is lacking...

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Detalhes bibliográficos
Main Authors: Schaetzlein, Sonja, Lucas-Hahn, Andrea, Lemme, Erika, Kues, Wilfried A., Dorsch, Martina, Manns, Michael P., Niemann, Heiner, Rudolph, K. Lenhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419552/
https://ncbi.nlm.nih.gov/pubmed/15148368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402400101
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