The Effects of IRE1, ATF6, and PERK Signaling on adRP-Linked Rhodopsins

by Chiang, Wei-Chieh Jerry, Lin, Jonathan H.
Published in Adv Exp Med Biol (2014)

IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

by Chiang, Wei-Chieh, Messah, Carissa, Lin, Jonathan H.
Published 2012

Endoplasmic Reticulum-Associated Degradation (ERAD) of Misfolded Glycoproteins and Mutant P23H Rhodopsin in Photoreceptor Cells

by Kroeger, Heike, Chiang, Wei-Chieh, Lin, Jonathan H.
Published 2012

Pathomechanisms of ATF6-Associated Cone Photoreceptor Diseases

by Chiang, Wei-Chieh Jerry, Kroeger, Heike, Chea, Lulu, Lin, Jonathan H.
Published in Adv Exp Med Biol (2019)

Selective Activation of ATF6 and PERK Endoplasmic Reticulum Stress Signaling Pathways Prevent Mutant Rhodopsin Accumulation

by Chiang, Wei-Chieh, Hiramatsu, Nobuhiko, Messah, Carissa, Kroeger, Heike, Lin, Jonathan H.
Published 2012

Endoplasmic Reticulum Stress in Human Photoreceptor Diseases

by Chan, Priscilla, Stolz, Julia, Kohl, Susanne, Chiang, Wei-Chieh, Lin, Jonathan H.
Published in Brain Res (2016)

ER stress and unfolded protein response in ocular health and disease

by Kroeger, Heike, Chiang, Wei-Chieh, Felden, Julia, Nguyen, Amanda, Lin, Jonathan H.
Published in FEBS J (2018)

Multiple Mechanisms of Unfolded Protein Response–Induced Cell Death

by Hiramatsu, Nobuhiko, Chiang, Wei-Chieh, Kurt, Timothy D., Sigurdson, Christina J., Lin, Jonathan H.
Published in Am J Pathol (2015)

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

by Chiang, Wei-Chieh, Joseph, Victory, Yasumura, Douglas, Matthes, Michael T., Lewin, Alfred S., Gorbatyuk, Marina S., Ahern, Kelly, LaVail, Matthew M., Lin, Jonathan H.
Published in Adv Exp Med Biol (2016)

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

by Alavi, Marcel V., Chiang, Wei-Chieh, Kroeger, Heike, Yasumura, Douglas, Matthes, Michael T., Iwawaki, Takao, LaVail, Matthew M., Gould, Douglas B., Lin, Jonathan H.
Published in Invest Ophthalmol Vis Sci (2015)

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

by Chiang, Wei-Chieh, Kroeger, Heike, Sakami, Sanae, Messah, Carissa, Yasumura, Douglas, Matthes, Michael T., Coppinger, Judith A., Palczewski, Krzysztof, LaVail, Matthew M., Lin, Jonathan H.
Published in Mol Neurobiol (2014)

Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop, in Genetic and Environmental Models of Retinal Degeneration

by Kroeger, Heike, Messah, Carissa, Ahern, Kelly, Gee, Jason, Joseph, Victory, Matthes, Michael T., Yasumura, Douglas, Gorbatyuk, Marina S., Chiang, Wei-Chieh, LaVail, Matthew M., Lin, Jonathan H.
Published 2012

De Novo Prion Aggregates Trigger Autophagy in Skeletal Muscle

by Joshi-Barr, Shivanjali, Bett, Cyrus, Chiang, Wei-Chieh, Trejo, Margarita, Goebel, Hans H., Sikorska, Beata, Liberski, Pawel, Raeber, Alex, Lin, Jonathan H., Masliah, Eliezer, Sigurdson, Christina J.
Published 2014

Achromatopsia mutations target sequential steps of ATF6 activation

by Chiang, Wei-Chieh, Chan, Priscilla, Wissinger, Bernd, Vincent, Ajoy, Skorczyk-Werner, Anna, Krawczyński, Maciej R., Kaufman, Randal J., Tsang, Stephen H., Héon, Elise, Kohl, Susanne, Lin, Jonathan H.
Published in Proc Natl Acad Sci U S A (2017)

The unfolded protein response regulator ATF6 promotes mesodermal differentiation

by Kroeger, Heike, Grimsey, Neil, Paxman, Ryan, Chiang, Wei-Chieh, Plate, Lars, Jones, Ying, Shaw, Peter X., Trejo, JoAnn, Tsang, Stephen H., Powers, Evan, Kelly, Jeffery W., Wiseman, R. Luke, Lin, Jonathan H.
Published in Sci Signal (2018)

Autosomal recessive cone-rod dystrophy can be caused by mutations in the ATF6 gene

by Skorczyk-Werner, Anna, Chiang, Wei-Chieh, Wawrocka, Anna, Wicher, Katarzyna, Jarmuż-Szymczak, Małgorzata, Kostrzewska-Poczekaj, Magdalena, Jamsheer, Aleksander, Płoski, Rafał, Rydzanicz, Małgorzata, Pojda-Wilczek, Dorota, Weisschuh, Nicole, Wissinger, Bernd, Kohl, Susanne, Lin, Jonathan H, Krawczyński, Maciej R
Published in Eur J Hum Genet (2017)

Multiexon deletion alleles of ATF6 linked to achromatopsia

by Lee, Eun-Jin, Chiang, Wei-Chieh Jerry, Kroeger, Heike, Bi, Chloe Xiaoke, Chao, Daniel L., Skowronska-Krawczyk, Dorota, Mastey, Rebecca R., Tsang, Stephen H., Chea, Leon, Kim, Kyle, Lambert, Scott R., Grandjean, Julia M.D., Baumann, Britta, Audo, Isabelle, Kohl, Susanne, Moore, Anthony T., Wiseman, R. Luke, Carroll, Joseph, Lin, Jonathan H.
Published in JCI Insight (2020)

A 45 nm Stacked CMOS Image Sensor Process Technology for Submicron Pixel †

by Takahashi, Seiji, Huang, Yi-Min, Sze, Jhy-Jyi, Wu, Tung-Ting, Guo, Fu-Sheng, Hsu, Wei-Cheng, Tseng, Tung-Hsiung, Liao, King, Kuo, Chin-Chia, Chen, Tzu-Hsiang, Chiang, Wei-Chieh, Chuang, Chun-Hao, Chou, Keng-Yu, Chung, Chi-Hsien, Chou, Kuo-Yu, Tseng, Chien-Hsien, Wang, Chuan-Joung, Yaung, Dun-Nien
Published in Sensors (Basel) (2017)

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

by Kohl, Susanne, Zobor, Ditta, Chiang, Wei-Chieh, Weisschuh, Nicole, Staller, Jennifer, Menendez, Irene Gonzalez, Chang, Stanley, Beck, Susanne C, Garrido, Marina Garcia, Sothilingam, Vithiyanjali, Seeliger, Mathias W, Stanzial, Franco, Benedicenti, Francesco, Inzana, Francesca, Héon, Elise, Vincent, Ajoy, Beis, Jill, Strom, Tim M, Rudolph, Günther, Roosing, Susanne, den Hollander, Anneke I, Cremers, Frans P M, Lopez, Irma, Ren, Huanan, Moore, Anthony T, Webster, Andrew R, Michaelides, Michel, Koenekoop, Robert K, Zrenner, Eberhart, Kaufman, Randal J, Tsang, Stephen H, Wissinger, Bernd, Lin, Jonathan H
Published in Nat Genet (2015)